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  1. I'm very curious, how many have seen obvious, negative psychological changes in your spouse immediately after taking Adderall? When my then alleged spouse of 19 years first took adderall, the change was very obvious, almost like she was possessed by a demon, no joke. I do know of others who have had similar experiences, and their spouse was not on any other prescriptions like antidepressants or narcotics. The adderall alone changed their spouses into strangers. After our divorce, I allowed her to remain in my house, to watch over our son and take care of our 7 cats and 2 dogs, most of them we rescued, had for over 2 to 9 years. When I traveled overseas, she EUTHANIZED ALL OF THOSE ANIMALS! These cats & dogs were like our children, what kind of person would do such a thing? This destroyed me.